God, AIDS, Africa & HOPE

Reflections / Gedanken

Sic tacuisses: AIDS = Justice – Belgian Catholic Archbishop of Brussels claims

The Catholic Church in Belgium has been battered by scandals and missteps over the past year, and now its new leader, the conservative Archbishop André-Joseph Léonard of Brussels, has sparked a fresh controversy with comments declaring that people afflicted with AIDS are receiving “a sort of immanent justice” for their sexual practices.
Léonard, who Pope Benedict XVI appointed this year to replace a much-loved liberal, Cardinal Godfried Danneels, compared the suffering of AIDS victims to human-caused degradation of the environment, for which people themselves then pay the price.
“Maybe human love also responds when she is treated badly, without the need of a transcendent source,” Léonard said in a just-published book of interviews he gave to two Belgian journalists over the past few years. “Badly handling physical nature causes it to treat us badly in turn, and badly dealing with the deeper nature of human love will ultimately always lead to catastrophes on all levels.”

The reaction against Léonard’s comments has been swift and sharp.

Belgian parliamentarians have called the archbishop’s statements “disgusting” and “stupid,” and some are calling for the government to re-examine the favorable tax status of the Catholic Church, which receives hefty government subsidies.
Even conservative Christian Democratic party leaders expressed outrage. Léonard’s words “strike me speechless. For Jesus there were no justified illnesses,” said parliamentarian Mia De Schamphelaere, according to a National Catholic Reporter story.
Such official condemnation comes at a difficult time for the Belgian church, which is engaged in a tug-of-war with government investigators who have seized documents in a probe of clergy abuse of children going back decades.
Léonard’s comments are also not winning him or the institutional church many points with Catholics themselves, who are increasingly indifferent to their religion, as is the case in many European countries.
The clergy scandals have shocked Belgians, with revelations of at least 475 victims over the decades, 13 of whom committed suicide. The reports brought down the country’s longest-serving bishop, Roger Vangheluwe, and even tarnished the legacy of Cardinal Danneels, whose negotiations with an abuse victim were surreptitiously recorded and released, portraying him in a harsh light.

Filed under: HIV and AIDS, , , , , , , ,

POZ Magazine: Forecasting the Future of HIV

As much as $722 billion might be needed to tackle HIV by 2031, if no cure or vaccine is found, according to new research published in The Lancet and reported by PlusNews. Study authors predict that in the next 20 years, annual HIV infections will be halved to about 1.2 million. However, new treatment guidelines will raise costs by 43 percent, and about one third of funding must be spent in Africa to stop the epidemic.  Researchers noted that the amount of money needed could drop to $400 billion if countries restructured their AIDS funding policies now.

To read the PlusNews story, click here.

Source: http://www.poz.com/rssredir/articles/Future_OF_HIV_1_19243.shtml

Filed under: HIV and AIDS, HIV Prevention, HIV Treatment, Medical and Research, Politics and Society, , , , , ,

14.10.2010 Days flying…

This week, time is flying because days are somehow booked out and between morning and evening lies one meeting after the other. I sometimes wonder how much one can take on different faces, different approaches, different worries, different joys until one mixes all up and is oneself mixed up – somehow..

But there is also success: the new HOPE Cape Town feature is done and on the way to Dresden – at the HOPE Gala in Dresden the feature will meet for the first time an interested audience.  HOPE Cape Town management meeting is gone and many issues solved, discussed, put onto the right track. The re-structuring of the organization to be more professional in its efforts to combine grass root and research is on the right path to realisation. My trip to Europe becomes more and more a detailed one with lots of interesting meetings and presentations, and in between two galas, one in Dresden (HOPE Gala Dresden) and one in Berlin (AIDS Gala Berlin). I will meet old friends and hopefully new future supporters of HOPE Cape Town. The expectations are always high and time will tell whether I am able to match my own ones..  🙂

And a big birthday celebration is in waiting: Brother Joachim – Joachim Franz – is turning 50 years in November and I am looking forward to a great evening full of laughter and joy. And at the same time some serious discussion for the World AIDS Awareness Campaign 2011 – beginning in April next year. A real challenge, watch the space. This block will report on every detail of this indeed challenging campaign.

This week saw also discussions about the future of CAN, the Catholic AIDS Network of the Archdiocese of Cape Town as well as the  future of POZ, the initiative of pastoral care for priests and religious living with the virus… Nothing is easy, nothing is set in stone, all developing and obviously at the end should stand nothing more than a meaningful service for fellow men.

Filed under: HIV and AIDS, HOPE Cape Town Association & Trust, Society and living environment, , , , , , , , ,

POZ Magazine: Therapeutic Vaccine Achieves “Functional Cure” in Monkeys

Therapeutic Vaccine Achieves “Functional Cure” in Monkeys

The monkey version of a therapeutic vaccine by VIRxSYS Corporation achieved a “functional cure”—fully controlling simian immunodeficiency virus (SIV) production and halting disease progression in a subset of vaccinated monkeys.
VIRxSYS has been pursuing gene therapy against HIV for several years, but it has been exploring a therapeutic vaccine as well. Its technology involves packaging HIV’s genetic material within a molecular delivery vehicle, commonly known as a vector. The company is using a lentivirus as the vector for its current vaccine, dubbed VRX1273.
As a step before human testing, VIRxSYS scientists gave a simian version of its VRX1273 vaccine or a placebo to several monkeys in their laboratory. After the monkeys were vaccinated, they were infected with a virulent strain of SIV. Gary McGarrity, PhD, executive vice president of scientific and clinical affairs at VIRxSYS, in Gaithersberg, Maryland, reported the results of this experiment at the AIDS Vaccine 2010 conference, which was held September 28 to October 1 in Atlanta.
Two of the five monkeys that received VRX1273 were able to maintain full control of SIV. In the placebo group, several of the monkeys died, providing evidence that VRX1273 both controls SIV reproduction in infected monkeys and provides a survival benefit.
“We and HIV key opinion leaders are very optimistic about these long-term results showing viral suppression, protection of the immune system and survival in this prophylactic study,” McGarrity said. “In addition, the full control of SIV replication following infection of two of our monkeys is a significant milestone in our research to develop effective therapeutic and prophylactic vaccines for HIV.”

Source:  http://www.poz.com/articles/hiv_virxsys_vaccine_761_19211.shtml

Filed under: HIV and AIDS, HIV Treatment, Medical and Research, Uncategorized, , ,

POZ Magazine: New Computer Modeling System Predicts Which HIV Combos Are Best

Researchers in London announced October 6 the launch of a free-of-charge, online computer modeling system to help providers choose the antiretroviral (ARV) combinations that will most likely work for their patients.

For people starting their first ARV regimen, the choices are usually pretty clear. Given that all of the combinations recommended by the Department of Health and Human Services HIV treatment guidelines panel have proved effective at controlling HIV, the choice usually comes down to which combination will be easiest to take and have the least troubling side effects.

For people who are on their third, forth or fifth regimens, however—or those who are infected with drug-resistant HIV—treatment decisions can be challenging. Currently, providers must sort through the often complex results of genotype tests, which identify the drug-resistant mutations a person’s HIV carries, along with a person’s treatment history to determine what combinations are most likely to work. In the most complex cases, providers often consult with resistance experts at university academic centers.

Now, a group of researchers belonging to a non-profit group called the Response Database Initiative has launched a new online computer modeling program to help providers make more accurate predictions about the best regimens for their patients. Called the HIV Treatment Response Prediction System (HIV-TRePS), the system uses computer simulations based on the medical records of over 70,000 people with HIV around the world to determine which treatments will be best for a specific individual.

To use the system, a provider enters a person’s genotypic test results, viral load, CD4 count and treatment history. Within seconds, the system returns to the provider a list of potential combinations, sorted by their potency and tolerability.

“This is a very exciting development—the system literally puts the experience of treating thousands of different patients at the doctor’s fingertips,” commented Julio Montaner, MD, from the BC Centre for Excellence in HIV & AIDS in Vancouver. “This has the potential to improve outcomes for people living with HIV and AIDS around the world, particularly where resources and expertise are scarce.”

HIV-TRePS is only about 78 percent accurate in its predictions, and its developers caution that it should not be substituted for expert medical guidance. It has, nevertheless, proven more effective than other available methods, which have about 54 percent accuracy, for predicting which regimens will be most likely to work.

“We are really excited about the launch of this system, which is a milestone for us, our research partners around the world and also for the use of bioinformatics in medicine,” said Brendan Larder, PhD, scientific chair of RDI. “We believe this approach can make a significant difference in a variety of settings and diseases.”

Source: http://www.poz.com/rssredir/articles/hiv_resistance_treps_761_19217.shtml

Filed under: HIV and AIDS, HIV Treatment, Medical and Research, , , ,

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