God, AIDS, Africa & HOPE

pensée of a Catholic priest

Signs of hope – remission without long-term treatment

At the recent conference of the International Aids Society in Paris it was a topic hotly discussed by academics, researchers and representatives of NGO’s:

A 9-year-old South African child diagnosed with HIV when he was 1 month old has been in HIV remission for 8½ years — without regular treatment. This is the first reported case of a child controlling their HIV infection without drugs in Africa and the third known case globally. The related research was conducted among others by Prof Dr Mark Cotton, board member of our HOPE Cape Town Association.

Soon after diagnosis, the child was placed on antiretroviral treatment, or ART, for 40 weeks, at which point treatment was stopped and the child’s health was monitored. Blood tests in late 2015 revealed the child is in HIV remission, meaning levels of the virus in the blood are undetectable using standard tests. Subsequent testing of samples dating back to the child’s infancy confirm remission was achieved soon after treatment was stopped. Treatment was paused as part of a larger research trial investigating the potential for early ART to decrease infant mortality and cut the need for lifelong treatment among newborns infected with HIV. “This is really very rare,” said Dr. Avy Violari, head of pediatric clinical trials at the Perinatal HIV Research Unit at the University of Witwatersrand in South Africa. Violari is the child’s doctor and presented the findings at the 9th International AIDS Society Conference on HIV Science in Paris

The child, not identified, was part of a study known as the Children with HIV Early Anti-retroviral Therapy, or CHER, trial, conducted in the years 2005 to 2011. More than 370 infants infected with HIV were randomly assigned to immediately receive ART for either 40 weeks or 96 weeks. A third group received no immediate treatment, but instead was looked after according to standard guidelines at the time. The CHER trial set out to investigate whether mortality rates could be reduced, but also whether earlier treatment could keep children healthy enough to enable them to come off treatment for certain periods. “We were hoping to make it a slower-progressing disease,” said Violari.

The study found mortality decreased by 76% and HIV disease progression reduced by 75% among the infants who received treatment immediately, for 40 or 96 weeks. The group receiving standard treatment saw an increase in mortality based on interim results, so that arm of the trial was stopped early. But virus levels in the 9-year-old case remained and remain undetectable. “The child is the only child showing remission,” said Violari. “We cannot see virus in the blood … we can see fragments of the virus in the cells,” she said, adding that these fragments appear not to be able to replicate, for now.

The South African child is the third reported case of long-term HIV remission in a child after early, limited treatment with antiretroviral drugs.

The first case was a Mississippi baby, a girl born in 2010, who received ART just 30 hours after birth until she was 18 months old, at which point HIV remission was achieved. The baby sustained remission for 27 months, until 2015, when she rebounded and the virus was found in her blood, crushing hopes that this approach could be the route to a “functional cure” for HIV. Next came the 2015 case of a French teenager, now 20, whose mother was HIV positive. The French child was given antiretroviral treatment soon after birth, stopped treatment at age 6 and has maintained undetectable levels of the virus in her blood since.

“We are delighted and excited by what happened with this child … we need to extrapolate from this to the benefit of other children on antiretroviral drugs,” said Prof Mark Cotton, Professor of Pediatrics at Stellenbosch University in South Africa, who co-led the study. “Africa is still the epicenter of the epidemic and more babies are acquiring HIV than anywhere else.”

Cotton hopes his team presenting these results will boost morale, both among cure researchers and those managing treatment programs for children across the continent.

More links:

Hope for future HIV cure revived
It is really very rare
Without drugs

Filed under: Africa, HIV and AIDS, HIV Treatment, HOPE Cape Town Association, HOPE Cape Town Association & Trust, Medical and Research, South Africa, , , , , , , , , , , , , , , ,

IAS conference 2017

Fragments of thoughts and impressions

It is my first IAS conference I have attended and compared with the World Aids conference it is a smaller crowd: round about 6000 people from all over the world coming in Paris together to discuss developments in the fields of HIV and Aids.

The first impression is that the conference is much more academic and discerning – it feels that most talks and presentations are indeed on a much higher academic level then at local Aids Conferences or the big world conference.

I am staying at a hotel outside Paris in Nanterre a commune in the Hauts-de-Seine department, the western suburbs of Paris. It is located some 11 km north-west of the centre of Paris. It feels strange – and from the beginning I can feel people have to live in a way which does not support human interaction – it feels cold, just doing the job of housing people without consideration on the human desire to live in a nice and friendly environment. It’s a sort of shock for somebody living in South Africa – it is strange but it feels like as soul-less place. The hotel is situated on top of a commuter train tunnel and station – every now and then one can feel the coming and going of a train while laying in bed.
So I guess all is there to sustain living and working, there are high rising buildings and all kind of services, but the thought I take with is that I can understand such suburbs create problems and even violence.

The mix of people here is amazing – mostly and certainly from the African region of Algeria, Tunisia and Morocco – it feels non-European in a European way – figure it out what it means.

And travelling to the conference centre – using the train and the metro – being part of a huge crowd in the morning and evening entering and exiting the dark alleys of the underground world – being part of the endless movements of people pushing their way through the crowd to reach their daily destiny – it is breath-taking – but not in the usual sense of the word. I definitely recall all my blessings living with some space and lots of day light in South Africa.

The conference itself is for a non scientific person sometimes difficult to follow – but I guess it is not about the exact details of every molecule one has to understand, the sheer feeling of understanding the principle – the idea behind all the details – the sometimes keen thoughts and trials and errors are a fascinating mental adventure – it stimulates my brain and forces me to read and study and “google”  – I have to admit that is a great experience to be beamed for a while into an environment really challenging you on knowledge and understanding.
But I believe that people running organisations must have at least a grasp about the background work done and the driving forces behind new developments before they reach the grass-root scene to be put into practice. Fruitful communication, bridging the gap between science and grass-root as HOPE Cape Town is trying to achieve on a daily base means for those in charge constant learning and communication with all spheres of their work environment.

Last but not least it was great meeting people from other countries and engaging in discussions – learning from each other and about each other and feeling the compassion of trying to rid the world of a viral onslaught. And yes, there is of course also lots of business – lots of calculation, but even there, you very often sense that those being employed in the big pharmaceutical companies understand that there is humanity needed in business. The connectivity of the global village, the threat that a virus can easily come and bite those far away helped indeed to change some of the attitudes which governed such entities a decade ago. Surely there is still lots to optimize and clarify – a balance must be put into place between commerce and humanity but I guess the battles of treatment have brought some clarity and movement into the field. Well, a watchful eye seems to be always necessary when it comes to that topic.

I will leave Paris tomorrow with lots of new understanding about the work done in the laboratories of this world. I leave proud knowing that our very board member of HOPE Cape Town, Prof Mark Cotton co-chaired the CHER study which produced one of the most published results of the conference: the child for 9 years in remission after being treated as a baby. I leave motivated knowing how many people dedicated their lives and career to fight back a pandemic which brought so much death and sorrow onto human mankind. It simply feels great to be part of a movement which has the goal to end a pandemic and give people a chance to live life and sexuality without fear. To live and to love to the utmost in their lifetime.

The only question I was wondering – how many other priests or clergy have been to this conference – not that it really matters but it would be nice to know that more of my fellow brothers are engaged on this level in a matter of live and death for millions in this world.

 

Filed under: General, HIV and AIDS, HIV Prevention, HIV Treatment, HOPE Cape Town Association & Trust, HOPE Cape Town Trust, Networking, Reflection, Society and living environment, South Africa, Uncategorized, , , , , , , , , , , ,

A new year for HOPE Cape Town – some thoughts…

With the 1st of March HOPE Cape Town is starting afresh in a new financial circle – the new budgets are approved and put into working, the old ones are closed and now made ready for the independent audit. Obviously the change in the currency exchange rate and so many other factors influence the outcome of budget planing – in our days it is getting more and more difficult to be as precise as possible. Therefore HOPE Cape Town is determined to follow true with the dream to have as much own capital as needed to pay all operations from the interest. It would take away the worries of constant fundraising, the constant knocking on doors which obviously also with all the reporting binds forces which could be used to aid those in need directly.

With HOPE for Babies in the maternity wards of Tygerberg Hospital the work with pregnant moms, delivering moms and then paediatric HIV to follow through with the kids infected and affected HOPE Cape Town compliments more and more its own goal to work with children from birth till they are matured in adulthood, only to come back as parents of newly born babies. The first 1000 days play a pivot role in having a holistic view and HOPE Cape Town is proud to be part of the program, the Western Province is pursuing to make sure that every newborn has the best chance in life possible in the framework of the circumstances he or she is born into. Re-visiting the Go-Box project to engage with young mothers and their babies in teaching them how to stimulate the little once with educational toys and education play adds to the bouquet of services.

Published research in national journals gives HOPE Cape Town the chance to showcase the results of best practice and to share this knowledge with those beyond the Western Cape boarders. Attending national and international conferences or, as just happened with our Program Coordinator doing an internship in a German paediatric hospital in Passau, adds to the possibilities to learn, share and being part of an international movement assisting children being infected, affected or having related illnesses or medical problems.

HIV and AIDS are topics which interconnect with so many other topics and portfolios. This lead for example to the founding of HOPE Cape Town USA – poverty, racism, the desire for Afro-Americans to find their African roots as well as infection rates are common areas to engage in a close working relationship with the USA.  Obviously also the chance to contribute as an US American to our work in South Africa is a welcomed component of this adventure. Many US students take a chance to engage with HOPE Cape Town when visiting South Africa on a field trip or excursion.

So, this small little entity called HOPE Cape Town connects three continents now: HOPE Kapstadt Stiftung in Bonn/Germany, HOPE Cape Town USA in Dallas/Texas and HOPE Cape Town Association & Trust in Cape Town / South Africa. The global family is growing slowly but substantially with all its challenges here in South Africa, but also to bring worlds together in a global village which seems in the moment so much driving apart. We hear about “America First” and all those funny slogans – HOPE Cape Town remains committed to “humanity first” and the organization will work tireless not only to serve those in need in the Western Cape but also to make sure that international understanding and care for each other stays a much-needed focal point.

Filed under: Africa, HIV and AIDS, HIV Prevention, HIV Treatment, HOPE Cape Town Association, HOPE Cape Town Association & Trust, HOPE Cape Town Trust, HOPE Cape Town USA, Medical and Research, Networking, Politics and Society, Reflection, Society and living environment, South Africa, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

World Aids Day 2016

o-world-aids-day-facebook“Leadership. Commitment. Impact” so the slogan for the World Aids Day 2016 which the world will celebrate coming week. Signs are already visible – newspapers and magazines are publishing more and more stories about HIV and AIDS, marketing prescribes for many products and messages the red ribbon – and as always on the 2nd of December some reviews will end the frenzy and hype around the pandemic. The world is getting quiet again till next year same time.

“Leadership. Commitment. Impact” – when I look around the world in our days – there is neither responsible leadership nor commitment prominently visible. The global village is rather falling apart in nations of own interest again, in the USA a racist and misogynist is elected president, in Turkey there is a dictator in the making and right-wing politicians worldwide gain popularity by only looking to create walls and distances between people. In South Africa President Zuma and the ruling party miss the boat of leadership completely and run the country into the ground if it continues like this.

Maybe we expect leadership and commitment from the wrong people and parties. Looking at the AIDS pandemic we can learn that leadership did not come from those in power. US President Reagan did everything possible to ignore the pandemic, church leaders – and some until today – were calling it the punishment of God – no, leadership came from those who were at the margins of society – in this case the gay people who organized in a committed way resistance against ignorance, demanded public attention and at the same time cared with passion and compassion about those about to lose their lives in mainly young age. Those, who were criminalized, ostracized, punished and outlawed fought the fight and brought at the end even a global political body like the UN to dedicate a meeting on a pandemic – a first in the history of the entity.

HIV and Aids brought so the attention of the global village not only to its own plight, but other sicknesses torturing those living in Africa and other far away areas as seen from Europe and the USA came under the spotlight. Even a global fond was established – another first in this regard. Maybe it needs a drama of that magnitude to bring people together – to let them forget about their own interests only and to realize the interconnections of human mankind and creation as such.
HIV and Aids are not sexy anymore – medication has stopped the immediate carnage and prolonged life in theory for all, in practice mainly for those able to afford it. Looking at the figures we see that too many people don’t have access to treatment and the infection rates are climbing disturbingly in some countries again while others – like South Africa – remain stuck on a high level. The Global Fund is struggling to maintain its impact as countries don’t honor their commitments or paying less and less believing the pandemic is under control. Looking at other viral and bacterial diseases we know that this is false hope. Life is a bitch – and evolution at work and if we don’t watch out, chances are high that we see reruns of battles we thought we have won long ago.

I wish that World Aids Day 2016 is more than just a reminder of the plight of HIV positive people. I hope that this day also serves as a beacon of hope that leadership is coming back, commitment is not only pledged but practiced – and not only in handing out medication or testing people, but also to create a surroundings and environment that let people living with HIV live without discrimination and with proper access to treatment and care in a peaceful setting. The global village needs an urgent reminder in our days that we respectfully need each other to create a future where diseases are healed, pandemics are maintained, not only those of the body but also of the hearts and souls and minds of people.

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HOPE Cape Town is working in a holistic way to give young people living with HIV and related illnesses hope and a future.
www.hopecapetown.com / www.hopecapetownusa.com

Filed under: Africa, General, HIV and AIDS, HIV Prevention, HIV Treatment, Medical and Research, Politics and Society, Reflection, Religion and Ethics, Society and living environment, South Africa, Uncategorized, , , , , , , , , , , , ,

Job Advertising HOPE Cape Town Association

HOPE Cape Town, a local non-profit Organisation providing outreach and education in the field of HIV and AIDS and related illnesses, seeks a full time medical doctor to co-manage the HOPE Doctor portfolio.
Responsibilities of this position include, but are not limited to:
* Clinical work
Provide comprehensive clinical care to HIV infected children at community based state health care facilities.
* Training
Manage the medical elective student program
Train and support the HOPE Community Health Workers
Provide external training and awareness as required
* Project management and support
Assist in planning, initiating and executing HOPE Cape Town Association projects and programs.
Act as Project leader for HOPE Cape Town projects.
* Research
Identify research opportunities; plan and implement formal and informal research
*Other
Interact with donors and media as required
Participate in HOPE Cape Town events

The HOPE Doctor will be based at both the Tygerberg Childrens Hospital Ithemba Office and the HOPE Cape Town offices at Tygerberg Campus, University of Stellenbosch, but will be required to travel to health care facilities and community based projects. The successful candidate will form part of senior staff team. This is a full time position (40 hours per week). He/She will report to the Program Coordinator.

Requirements:
* M.B.Ch.B (Bachelor of Medicine and Bachelor of Surgery)
* Valid Registration with HPCSA (Health Professions Council South Africa)
* Registration with MPS (Medical Protection Society)
* Excellent interpersonal skills
* Superior Communication Skills: Fluent in English (spoken and written); other languages an asset
* Advanced computer skills (Microsoft Office)
* Drivers licence with independent transport
* No criminal record
* Work permit (if not SA resident)

The following experience and skills would be advantageous:
* At least one year’s experience in managing HIV positive patients on ARV treatment (including children)
* Diploma in HIV Management of college of family physicians of South Africa (Dip HIV Man (SA))
* Research experience

Applications should include a covering letter detailing each of the identified qualifications and skills, proof of qualifications and a current CV and a minimum of two references. Completed applications may be forwarded
To: Dr Izane Reyneke
HOPE Cape Town
P.O. Box 19145, Tygerberg 7505 Cape Town – South Africa; Phone 021 – 938 9930
Email program@hopecapetown.com
Suitable candidates will be invited for an interview
Closing date for applications: 14 August 2016

To print the advert use the following link:

HOPE Cape Town Job Ad -Fulltime medical doctor 2016

Filed under: Africa, HIV and AIDS, HIV Prevention, HIV Treatment, HOPE Cape Town Association, HOPE Cape Town Association & Trust, HOPE Cape Town Association & Trust, Medical and Research, South Africa, Uncategorized, , , , , , , , , , , ,

12th HOPE Gala Dresden

HOPE Gala Dresden - the event to be in DresdenOctober 28th, 2017
12 days to go.

Ball of HOPE 2018

Join us @ The Westin in Cape TownMay 12th, 2018
6 months to go.

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© Rev Fr Stefan Hippler and HIV, AIDS and HOPE.
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