God, AIDS, Africa & HOPE

Reflections / Gedanken

POZ Magazine: Beijing AIDS Group Forced to Close

Beijing AIDS Group Forced to Close

Beijing Loving Source, an AIDS service organization, will close operations following increased pressure from tax authorities in the Chinese government, The Associated Press (AP) reports. The group was founded by Hu Jia, a well-known AIDS activist who is currently serving a 3.5 year prison sentence for pushing authorities to deal with HIV publicly. After the government started regulating overseas donations, the organization ran into financial troubles.

To read the AP article, click here

http://www.poz.com/rssredir/articles/AIDS_Beijing_ASO_1_19395.shtml

Filed under: HIV and AIDS, Politics and Society, , , ,

07.11.2010 AIDS Gala Berlin – and where is the bishop?

Again, I am guest at the German AIDS Gala in Berlin, the 17th of its kind. And again the German Oper Berlin is booked out and masses of people are flocking to attend this prestigious event. Michaela from Dresden is accompanying me to this event and after being picked up by the Shuttle Service at the hotel, it is once again a funny feeling to take the red carpet, letting the journalists and photographers guess who the couple is.. 🙂 Being asked how I felt about the feature of myself and HOPE Cape Town in the Berliner Morgenzeitung I must admit that I even didn’t know about it – nobody told me. Quick I realise that HOPE Cape Town will feature prominently this eve as one of the projects sponsored by the German AIDS Foundation. Brief chats with Her Highness, the Begum Aga Khan, the National foreign Minister Guido Westerwelle and his husband and others from the Board of Trustees follow before the programme starts. And as now expected, the chairperson of the board of trustees of the German AIDS Gala in Berlin, the Begum Aga Khan tells the audience about her visit at HOPE Cape Town last year – a film shows her and me visiting the Ithemba Ward and I wish all our HOPE Community Health Workers, senior staff and management could hear the applause as she congratulates the projects and the priest for their work down there in the Western Cape. These are moments were I would love to beam myself away for the time being – sometimes it is interesting enough for me difficult to hear public praise. But it is also the feeling of encouragement present.

The programme contains great opera – I do enjoy it and when the Opera Children’s choir sings “Laudate Domino” I suddenly realise that there is no official representative of the church. And if feels suddenly so completely wrong: National ministers, certainly all important people of the local and national business world, politicians and artists are present – showing their committment towards the battle against a pandemic which changed the world – celebrating also partly a project, which originated and is still support by a German-speaking Catholic community and no representative of my church is present. And I suddenly realise that also in Dresden the last five years there was no-show of the local bishop or his representative. The sorrows and the joy of the people are the sorrows and the joy of us Christians – I ask myself whether it is not poor judgement to be not present visible as a church at major events where people from so different walks of life unify and come together in this important cause. I suddenly feel sad a moment, but then the joy of the choir carries me away from it.

Congratulations to the German AIDS Foundation and all its helper for this great eve – and I am grateful that within one week I am able to attend to major fundraising galas bringing hope and future again to South Africa. A big part of the proceeds of Berlin are also going to HOPE Cape Town and supporting our work. Deo gratias.

Filed under: HIV and AIDS, HOPE Cape Town Association & Trust, Medical and Research, Networking, Reflection, Society and living environment, , , , , , , , , , , , , , ,

20.10.2010 Podium Discussion

Yesterday evening at the Centre of the Book: Podiums discussion about ” A new South African HIV/AIDS policy: Reason for HOPE?.

Nozizwe Madlala-Routledge, Deputy Minister of Defence (1999-2004) and Deputy Minister of Health (2004-2007) and Chris Bateman,  Senior Editor of the SA Journal of Medicine and myself are discussing the new policy and the role, politics and civil society must play so that the new HIV/AIDS policy becomes reality. An interesting debate about the possibilities and limitations of the New South Africa and its leaders, but also the misery and burden of ordinary South Africans. The questions of the audience give room for a brought debate from trips to the bilateral German – South African agreement versus a contribution to the Global AIDS Fund, but also practical question how hope can be brought to certain communities and a perspective on life worth living and striving for.

An interesting evening where also the president’s life and the topic “leading by example” was not spared some honest comments. Last but not least the question why South Africa pays 20% above the cheapest market price for ART medication produced by Aspen and all the red tape stopping to make cheaper and more meaningful solutions possible.

Filed under: HIV and AIDS, HIV Prevention, HIV Treatment, Politics and Society, , , , , , , , , ,

POZ Magazine: New Computer Modeling System Predicts Which HIV Combos Are Best

Researchers in London announced October 6 the launch of a free-of-charge, online computer modeling system to help providers choose the antiretroviral (ARV) combinations that will most likely work for their patients.

For people starting their first ARV regimen, the choices are usually pretty clear. Given that all of the combinations recommended by the Department of Health and Human Services HIV treatment guidelines panel have proved effective at controlling HIV, the choice usually comes down to which combination will be easiest to take and have the least troubling side effects.

For people who are on their third, forth or fifth regimens, however—or those who are infected with drug-resistant HIV—treatment decisions can be challenging. Currently, providers must sort through the often complex results of genotype tests, which identify the drug-resistant mutations a person’s HIV carries, along with a person’s treatment history to determine what combinations are most likely to work. In the most complex cases, providers often consult with resistance experts at university academic centers.

Now, a group of researchers belonging to a non-profit group called the Response Database Initiative has launched a new online computer modeling program to help providers make more accurate predictions about the best regimens for their patients. Called the HIV Treatment Response Prediction System (HIV-TRePS), the system uses computer simulations based on the medical records of over 70,000 people with HIV around the world to determine which treatments will be best for a specific individual.

To use the system, a provider enters a person’s genotypic test results, viral load, CD4 count and treatment history. Within seconds, the system returns to the provider a list of potential combinations, sorted by their potency and tolerability.

“This is a very exciting development—the system literally puts the experience of treating thousands of different patients at the doctor’s fingertips,” commented Julio Montaner, MD, from the BC Centre for Excellence in HIV & AIDS in Vancouver. “This has the potential to improve outcomes for people living with HIV and AIDS around the world, particularly where resources and expertise are scarce.”

HIV-TRePS is only about 78 percent accurate in its predictions, and its developers caution that it should not be substituted for expert medical guidance. It has, nevertheless, proven more effective than other available methods, which have about 54 percent accuracy, for predicting which regimens will be most likely to work.

“We are really excited about the launch of this system, which is a milestone for us, our research partners around the world and also for the use of bioinformatics in medicine,” said Brendan Larder, PhD, scientific chair of RDI. “We believe this approach can make a significant difference in a variety of settings and diseases.”

Source: http://www.poz.com/rssredir/articles/hiv_resistance_treps_761_19217.shtml

Filed under: HIV and AIDS, HIV Treatment, Medical and Research, , , ,

POZ Magazine: Considering Cannabis – e.g. USA

In states where it is legal, medical marijuana helps some HIV-positive people cope with living their lives.

In the states of California and Washington, since 1996 and 1998, respectively, medical marijuana has been legally available for people with HIV, cancer and other serious health challenges. Heading west this past spring from my home in Connecticut, I set out to learn about the states’ medi-pot programs. Okay, I admit it. I also hoped to score a bit of medicine, too.
Nationally, 14 states plus the District of Columbia allow medical marijuana use. Most of these consider anyone with HIV/AIDS eligible for medical pot. Many HIV-positive people use marijuana to treat nausea, appetite loss, the pain of neuropathy, chronic bowel problems and even anxiety. “When appropriately prescribed and monitored,” the American Academy of HIV Medicine stated in 2007, “marijuana/cannabis can provide immeasurable benefits for the health and well-being of our patients.”

So it is not surprising that some people with HIV use marijuana for medical purposes, whether it’s legal or not. And a whopping 89 percent of the men participating in the long-term Multicenter AIDS Cohort Study (MACS) acknowledged using pot, though they weren’t asked whether it was legally obtained.  In Seattle, I interviewed Robert Wood, MD, recently retired AIDS chief for the Seattle/King County public health department. Based on his experience, which dates to the early 1980s, Wood said pot helps many positive people in the aforementioned ways. And while it seems to help some people sleep, he noted, it can have the opposite effect for others.  John Moore, a San Francisco man living with HIV since 2004, told me his doctor recommended pot to treat lipoatrophy. “Weed does not help lipoatrophy [a condition that results in loss of body fat], OK?” he said, fairly winking. But it can alleviate the emotional impact of lipo and other HIV side effects. “It provides a sense of well-being and allows me to get away temporarily from anxieties,” Moore said. “Some would say it’s an illusion, but so what? I think we should be looking at it like any other medicinal substance.”

Indeed, the placebo effect can be useful. As Josiah Rich, MD, professor of medicine and community health at Brown Medical School at Providence, Rhode Island, said: “Whether the benefit is from marijuana or from the belief that it is helping, it has a real effect for some people suffering from symptoms related to HIV or HIV meds.”  The road to legalization has been long. In 1999, the Institute of Medicine, which advises the federal government on scientific matters, asserted “the potential therapeutic value for cannabinoid drugs.” But it took until last year for the American Medical Association to sign on. Moreover, federal law still outlaws marijuana. But in 2009, the justice department directed prosecutors to lay off people using medical cannabis in states where it’s legal. In San Francisco, the city instructed the police department not to arrest people for having medical marijuana. Apparently, the directive worked. “I get on the bus in the morning,” Moore said, “and the whole thing reeks of weed because so many people are carrying it.”
Unfortunately for me, California, like all the other medical pot states, limits the use of legal marijuana to state residents. Only a few states offer reciprocity for visitors from other legal-marijuana states who run out of medicine.
Obtaining medical pot is a pretty standard process for residents of the states offering it. First, you need a doctor’s medical recommendation (not a prescription). If having HIV isn’t enough, your doctor will want to know what specific ailments you are trying to address.
The referral—and a fee, ranging from $100 in Michigan to $150 in Nevada—will get you a one-year, state-issued ID card, usually from the state health department. Some states have dedicated medical pot offices, such as Vermont’s Marijuana Registry. The ID card allows you to avoid arrest and—important for people with compromised immune systems—avoid low-quality marijuana, possibly mixed with mystery compounds. You might pick up your new medicine in a state-licensed dispensary or “compassion center,” as Rhode Island calls them. In most states, a license also entitles you to grow a limited amount of pot. (See sidebar for further details.) Moore described the San Francisco dispensary he uses as a trailer-type building—like a teashop, but with bulletproof glass. “Behind [that] glass,” he explains, “is a woman sitting with a cash register. A white board on the wall lists what they have. Then there are big jars with different types [of cannabis]”—bearing names such as Purple Haze and White Widow. “Everything is priced by an eighth of an ounce,” Moore said. Prices are as high as $60 for high-quality grass, to a mere $20 for what’s commonly called “shake,” the stems and seeds that can be added to melted butter to make a spread. Insurance companies and third-party payers won’t (yet?) pay for medical marijuana, so it’s all out of pocket.

I didn’t see the dispensary, but Moore did take me into a smoke shop on 18th Street, half a block from the intersection of Castro, and pointed out the shelf of vaporizers. Instead of smoking, he uses one of these. “You put the weed in this little mesh chamber at the end of a short hose,” he said. “And you attach that above a heating element that heats but does not burn the herb, then inhale from the other end.“  Smoking pot can harm the lungs, the Institute of Medicine first warned in 1999. In contrast, vaporizers produce “little or no exposure” to the unhealthy chemicals smoking generates, including carbon monoxide and benzene, according to University of California at San Francisco researchers, led by longtime HIV and cancer doctor Donald Abrams, MD. What’s more, they found that a vaporizer produced higher plasma levels of THC (tetrahydrocannabinol, marijuana’s 
active ingredient) than smoking. Back in Providence, in his HIV clinic, Josiah Rich recommends a vaporizer to avoid lung damage. “But,” he adds, “smoking small amounts is not unreasonable.” In the name of research, I tried a vaporizer. As promised, the device eliminates the coughing and irritation associated with smoking weed. Beyond the known risks of smoking, there’s been at least a squeak of a warning about cannabis for people with HIV—from a “humanized” mouse. Researchers at UCLA infected a specially engineered mouse with an HIV-like virus, then gave it THC. They concluded the cellular damage they observed could mean that THC might slightly speed up the progress of untreated HIV. But Abrams found that neither smoked nor synthetic THC—dronabinol, in prescription Marinol tablets—affects viral load or interacts with HIV meds. In fact, he said, the research shows that marijuana “actually improved immune function after 21 days of smoking three times a day.” And so far, no other research has confirmed those mousy data. All medications have side effects and trade-offs. For example, the side effects of the HIV meds I take are diarrhea, headache, nausea, stomach pain or upset, tiredness, vomiting and weakness. By contrast, marijuana, whose most common side effect is “euphoric mood,” stacks up amazingly well.
Source: http://www.poz.com/articles/Medical_Marijuana_HIV_2521_18907.shtml

Filed under: HIV and AIDS, HIV Treatment, Medical and Research, Politics and Society, , , , , ,

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