God, AIDS, Africa & HOPE

Reflections / Gedanken

HIV vaccine completes phase I trial

The time-course of an immune response begins w...

The time-course of an immune response begins with the initial pathogen encounter, (or initial vaccination) and leads to the formation and maintenance of active immunological memory. (Photo credit: Wikipedia)

Sometimes there are good news one comes across while doing the early morning snatch on news on the internet  – news which just give this ray of hope. This one is certainly giving this ray of hope, even if success is still in the dark and not guaranteed. It’s about a vaccine, called SAV001-H, the result of a collaboration between Western University in London, Ontario, and Sumagen Canada Inc. In a randomized, observer-blinded, placebo-controlled study, the team examined the vaccine’s safety, tolerability and immune responses in HIV-positive adults between the ages of 18 and 50. And guess what: no significant adverse side effects discovered during trial period and researchers found that, following vaccination, the antibody against HIV’s p24 capsid antigen increased by a factor as great as 64 and the antibody against the virus’s gp120 surface antigen rose up to eightfold. These levels remained raised throughout the year-long study period.

This is good news on several layers: First of all there are people out there working on a vaccine and don’t give up. Second there will be now trial phase II. And there is an invitation attached: “We are opening the gate to pharmaceutical companies, government and charity organization for collaboration to be one step closer to the first commercialized HIV vaccine”, so Jung-Gee Cho, CEO of Sumagen.

Well, let’s support such efforts by all means possible.  And if one is interested to read more on the subject click here.

Filed under: HIV Prevention, HIV Treatment, Medical and Research, , , , , , , ,

HIV & TB: Supply problems in South Africa

English: Coat of Arms of South Africa Deutsch:...

English: Coat of Arms of South Africa – Wikipedia)

HIV activist groups in South Africa are calling on the Minister of Health to address drug supply chain problems which are causing HIV and tuberculosis (TB) drug stock-outs in the country’s Eastern Cape province. According to a report launched at the 6th South African AIDS Conference by a coalition consisting of the Rural Health Advocacy Project (RHAP), Doctors Without Borders (MSF), the Treatment Action Campaign (TAC) and SECTION 27, 40% of the 70 facilities surveyed by MSF and TAC during May 2013 in the Mthatha catchment area in the Eastern Cape province had experienced HIV and/or TB drug stock-outs. More than 100,000 people, on antiretrovirals (ARVs) or TB treatment, depend on 300 facilities served by the Mthatha depot. Medical staff at 24% of the affected facilities were forced to send patients home without treatment because they experienced stock-outs of essential HIV and TB drugs. These stock-outs were reported to last, on average, 45 days at a time and have been ongoing since October 2012. The organisations estimated that at least 5494 adults were not able to take some of their ARVs and 561 children were sent home without treatment since September 2012 when the drug supply issues began. Lamivudine (3TC), tenofovir, nevirapine, efavirenz, paediatric ARV formulations and Rifafour (a fixed-dose combination of four TB drugs) are the main medications affected. “This situation is catastrophic. It means many thousands of people living with HIV have risked treatment interruption for months now. The stock-outs consequently undermine clinical benefits of life-saving ARV treatment. Over time, more deaths will occur as a result and the likelihood of increased drug resistance is significant,” says Dr Amir Shroufi, Deputy Medical Co-ordinator for MSF in South Africa. There have been a number of reports of patients receiving dual or even monotherapy in the Eastern Cape and Gauteng. “I have been taking ARVs since 2008. Each year this [a stock-out] happens at least six times. I go to the clinic and they tell me there is no medication for me,” said a 36 year-old unemployed man who lives in a rural village in the Eastern Cape. “It is very difficult for patients. We are telling them to adhere, but when they arrive at the clinic, which can take up to two hours to access by car in the rural Eastern Cape areas, they are told there is nothing for them and that they must come back another time,” said Vuyokazi Gonyela, the TAC Eastern Cape District Organiser. On 10 October 2012, staff at Mthatha depot in the Eastern Cape staged a strike, following which 29 individuals were suspended, leaving the depot with only 10 working employees. Coupled with chronic supply chain issues, this precipitated widespread drug stock-outs in the region. The survey followed an intervention by MSF and TAC volunteers during December 2012, which continued for three months, to respond to the burgeoning Mthatha depot crisis by supporting staffing, managing and ensuring drug delivery at the depot. This intervention helped to clear the backlog of drug orders and to bring the depot closer to normal levels of functioning. “The MSF/TAC emergency intervention in the Mthatha depot from December 2012 to March 2013 has shown that it is possible to correct a disastrous situation with limited resources, even if the impact remains short-lived without large systemic  changes and action from the provincial Department of Health”, said Gonyela, who led the intervention. The main causes for the drug supply problems are the lack of an early warning system for facilities to be able to report potential shortages, drug suppliers failing to meet tender quotas, government failing to pay suppliers, and poor ordering practices at health facilities and medicine depots. South Africa has one of the largest ARV programmes in the world with over 2 million people initiated on ARVs in the public sector. However, drug stock-outs are occurring across the country and are not limited to HIV and TB medication, but extend to other basic chronic medication such as hypertension (blood pressure) and diabetes medication, according to Dr Francois Venter, Deputy Director of the Wits Reproductive Health and HIV Institute (WHRI). This was reiterated by a number of healthcare workers attending the conference. “The national Department of Health should create an emergency team to respond to stock-outs – given the extent, importance, and frequency of essential drugs stock-outs nationwide,” said John Stephens of SECTION 27. The organisations are recommending that when stock-outs are identified, the underlying reasons must be established for each and appropriate action undertaken, and the individuals responsible for the stock-outs must be clearly identified. In response to the drug supply problems, the organisations have set up a civil society monitoring group which will focus on solving the drug supply problems and continue monitoring drug supply across the country. “We are aware of the drug stock-outs across the country and share your concerns,” said Helecine Snyman, Head of Affordable Medicines at the South African Department of Health.

© Copyright NAM — All rights reserved. Please photocopy and pass on.

Filed under: HIV and AIDS, HIV Prevention, HIV Treatment, Politics and Society, , , , , , , , , , , , , , , ,

Syria is on everybodies mind

English: View of the main (and oldest) buildin...

English: View of the main (and oldest) building of Deir Mar Musa al-Habashi or Monastery of Saint Moses the Abyssinian, Syria Français : Vue du bâtiment principal (et le plus ancien) du monastère de Mar Mousa, Syrie (Photo credit: Wikipedia)

Nobody listening to the news can avoid being drawn into thoughts about Syria and the pending attack of US forces. History repeats itself – even if on a lighter scale as with Iraq. I am completely opposed to violence when it ignites more hate, more violence  and only serves the ego of US presidents or there-likes. “God’s own nation” is, like “God’s chosen people” again at the center of inflicting more pain to ordinary people instead of healing wounds. I am not naive and I don’t think that “always being nice and letting go” is the answer to all the injustice of this world. But if I can’t see any purpose for the good of the people, there can only be opposition.  I have been to Syria many times and always enjoyed the hospitality of these great people – they deserve better than what the world has to offer them in the moment. We humans have only the UN as an overwriting body – and yes, it is weak and full of failures, but this is the best we have in the moment and instead of ignoring it, we should better it. And for President Obama once again: Give back your Peace Nobel Price – you don’t deserve it.

Here the sermon of Pope Francis from yesterday,which says it all.

“’And God saw that it was good’. The biblical account of the beginning of the history of the world and of humanity speaks to us of a God who looks at creation, in a sense contemplating it, and declares: ‘it is good’. This, dear brothers and sisters, allows us to enter into God’s heart and, precisely from within him, to receive his message. We can ask ourselves: what does this message mean? What does it say to me, to you, to all of us?

“It says to us simply that this, our world, in the heart and mind of God, is the ‘house of harmony and peace’, and that it is the space in which everyone is able to find their proper place and feel ‘at home’, because it is ‘good’. All of creation forms a harmonious and good unity, but above all humanity, made in the image and likeness of God, is one family, in which relationships are marked by a true fraternity not only in words: the other person is a brother or sister to love, and our relationship with God, who is love, fidelity and goodness, mirrors every human relationship and brings harmony to the whole of creation. God’s world is a world where everyone feels responsible for the other, for the good of the other. This evening, in reflection, fasting and prayer, each of us deep down should ask ourselves: Is this really the world that I desire? Is this really the world that we all carry in our hearts? Is the world that we want really a world of harmony and peace, in ourselves, in our relations with others, in families, in cities, in and between nations? And does not true freedom mean choosing ways in this world that lead to the good of all and are guided by love?

“But then we wonder: Is this the world in which we are living? Creation retains its beauty which fills us with awe and it remains a good work. But there is also ‘violence, division, disagreement, war’. This occurs when man, the summit of creation, stops contemplating beauty and goodness, and withdraws into his own selfishness.

“When man thinks only of himself, of his own interests and places himself in the centre, when he permits himself to be captivated by the idols of dominion and power, when he puts himself in God’s place, then all relationships are broken and everything is ruined; then the door opens to violence, indifference, and conflict. This is precisely what the passage in the Book of Genesis seeks to teach us in the story of the Fall: man enters into conflict with himself, he realizes that he is naked and he hides himself because he is afraid, he is afraid of God’s glance; he accuses the woman, she who is flesh of his flesh; he breaks harmony with creation, he begins to raise his hand against his brother to kill him. Can we say that from harmony he passes to ‘disharmony’? Can we say this: that from harmony he passes to ‘disharmony’? No, there is no such thing as ‘disharmony’; there is either harmony or we fall into chaos, where there is violence, argument, conflict, fear.

“It is exactly in this chaos that God asks man’s conscience: “Where is Abel your brother?” and Cain responds: ‘I do not know; am I my brother’s keeper?’. We too are asked this question, it would be good for us to ask ourselves as well: Am I really my brother’s keeper? Yes, you are your brother’s keeper! To be human means to care for one another! But when harmony is broken, a metamorphosis occurs: the brother who is to be cared for and loved becomes an adversary to fight, to kill. What violence occurs at that moment, how many conflicts, how many wars have marked our history! We need only look at the suffering of so many brothers and sisters. This is not a question of coincidence, but the truth: we bring about the rebirth of Cain in every act of violence and in every war. All of us! And even today we continue this history of conflict between brothers, even today we raise our hands against our brother. Even today, we let ourselves be guided by idols, by selfishness, by our own interests, and this attitude persists. We have perfected our weapons, our conscience has fallen asleep, and we have sharpened our ideas to justify ourselves. As if it were normal, we continue to sow destruction, pain, death! Violence and war lead only to death, they speak of death! Violence and war are the language of death!

“After the chaos of the Flood, when it stopped raining, a rainbow appeared and the dove returned with an olive branch. I think also of the olive tree which representatives of various religions planted in Plaza de Mayo, in Buenos Aires, in 2000, asking that there be no more chaos, asking that there be no more war, asking for peace.

“And at this point I ask myself: Is it possible to walk the path of pace? Can we get out of this spiral of sorrow and death? Can we learn once again to walk and live in the ways of peace? Invoking the help of God, under the maternal gaze of the Salus Populi Romani, Queen of Peace, I say: Yes, it is possible for everyone! From every corner of the world tonight, I would like to hear us cry out: Yes, it is possible for everyone! Or even better, I would like for each one of us, from the least to the greatest, including those called to govern nations, to respond: Yes, we want it! My Christian faith urges me to look to the Cross. How I wish that all men and women of good will would look to the Cross if only for a moment! There, we can see God’s reply: violence is not answered with violence, death is not answered with the language of death. In the silence of the Cross, the uproar of weapons ceases and the language of reconciliation, forgiveness, dialogue, and peace is spoken. This evening, I ask the Lord that we Christians, and our brothers and sisters of other religions, and every man and woman of good will, cry out forcefully: violence and war are never the way to peace! Let everyone be moved to look into the depths of his or her conscience and listen to that word which says: Leave behind the self-interest that hardens your heart, overcome the indifference that makes your heart insensitive towards others, conquer your deadly reasoning, and open yourself to dialogue and reconciliation. Look upon your brother’s sorrow – I think of the children, look upon these – look upon your brother’s  sorrow, and do not add to it, stay your hand, rebuild the harmony that has been shattered; and all this not by conflict but by encounter! May the noise of weapons cease! War always marks the failure of peace, it is always a defeat for humanity. Let the words of Pope Paul VI resound again: ‘No more one against the other, no more, never! … war never again, never again war!’. ‘Peace expresses itself only in peace, a peace which is not separate from the demands of justice but which is fostered by personal sacrifice, clemency, mercy and love’. Forgiveness, dialogue, reconciliation – these are the words of peace, in beloved Syria, in the Middle East, in all the world! Let us pray for
reconciliation and peace, let us work for reconciliation and peace, and let us all become, in every place, men and women of reconciliation and peace! Amen”.

Filed under: Catholic Church, General, Politics and Society, Reflection, Religion and Ethics, , , , , , , , , , , , , ,

And another thought of being undetectable & on treatment

Chronic Disease

Chronic Disease (Photo:tamahaji)

Dave R. from TheBody.com is reflecting on the question of undetectable and what it would mean for those being infected. There are recommendations but there is no certainty. There might be certainty after further studies and in the moment it looks good for those who say that being undetectable, on treatment and no STI’s are not infectious anymore. Have you ever thought what this would mean for those being HIV positive? It would mean that HIV treated proper would be equal like having cancer, being a diabetic and having any other chronic disease.  If, after indisputable proof, it would be widely reported that people on successful treatment are not in danger of passing on the virus, then there is no reason for every sexually active person on the planet not to get tested and if necessary treated because treatment will make you a safe person to have sex with. It would be a great argument for getting tested and on treatment. And it would diminish the stigma attached still to this condition. Undetectable = not infectious: this would change perception and consequences of HIV and AIDS. To read the interesting reflection of Dave R. click here.

Filed under: HIV and AIDS, HIV Prevention, HIV Treatment, Medical and Research, Politics and Society, Reflection, Religion and Ethics, Society and living environment, , , , , , , , ,

New Job offers for HOPE Cape Town – Closing date: 15.09.2013

HOPE Cape Town is offering the following posts:

Position as a secretary for the back office of the HOPE Cape Town Association and Trust:
Position Secretary – HOPE Cape Town Association & Trust

Position as a resource developer for the back office of the HOPE Cape Town Association and Trust
Resource developer 2013

Applications should include a covering letter detailing each of the identified qualifications and skills, proof of qualifications and a current CV and a minimum of two references. Completed applications may be forwarded

To:
Kerstin Behlau
HOPE Cape Town Trust & Association
University of Stellenbosch, Tygerberg Campus 7th floor,
Clinical Build
ing, Faculty of Medicine and Health Sciences
P.O. Box 19145, Tygerberg 7505 Cape Town – South Africa
Phone 021 – 938 9930
Fax 021 – 938 6662
Email
admin@hopecapetown.com

 Suitable candidates will be invited for an interview

 Closing date for applications: 15 September 2013

Filed under: Uncategorized

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