God, AIDS, Africa & HOPE

Reflections / Gedanken

POZ magazine: Internet based HIV care

A group of HIV-positive people who received their health care via the Internet from a Barcelona HIV clinic felt that their care was comparable with—and potentially superior to—standard in-person care. These findings, published January 21 in the online journal PLoS One and reported March 21 on the website Computerworld, could offer hope to select patients in rural settings who must often travel great distances to receive specialty HIV care. By necessity, providers in resource-poor nations have been quick to adopt electronic communications as ways to provide health care. In countries where people are sometimes more likely to have access to a cell phone than running water or transportation, and where they must sometimes travel 100 miles or more to see a doctor, “e-medicine” has significantly expanded the reach of traditional health care.
Developed countries, including the United States, have been much slower to adopt these new technologies, partially because of concerns that e-medicine would result in poorer care, along with legal concerns about patient privacy. Recent positive experiences with using the Internet and telephones to extend and improve care for people with chronic diseases, such as diabetes, are beginning to tear down the walls that have kept e-medicine from wider implementation.
To determine whether e-medicine could be used in caring for people with HIV, Agathe León, MD, from the University of Barcelona, in Spain, and her colleagues set up a virtual hospital system in 2005 to help streamline care for patients in their HIV clinic. During the first two years of operation, León’s team tested its Internet-based system involving 83 HIV-positive people who were in stable health and had CD4s over 250. The study did not require participants to have an undetectable viral load or to be on antiretroviral (ARV) therapy—though about half were. All participants had a home computer and broadband Internet access.
Over the first year of the study, half of the group received their HIV care, pharmacy consultations, psychological care and appointments with social workers over the computer, while the other half received traditional in-person service. After one year, the groups switched their mode of receiving care. Participants went into local laboratories for any necessary lab work.

León’s team conducted detailed surveys of the participants throughout the study to assess their satisfaction with the care, their psychological health and their quality of life. Each participant’s CD4 count and viral loads were also recorded.
León and her colleagues found that patient satisfaction was high and that overall health and well-being—including CD4 counts and viral loads—were no different between those receiving care through the virtual hospital and those being seen at the clinic. This held true despite the facts that 7 percent started antiretroviral (ARV) therapy during the course of the study and 28 percent switched therapy. In fact, 85 percent reported that the Internet-based system actually made it easier for them to access the care they needed from their providers.
León reported that 200 people with HIV have now been followed through the virtual hospital.
“This program allows patients to continue their treatment without altering their routine. Medication is sent to their home, or other locations specified by the patient,” representatives for León’s clinic stated. “Telemedicine is emerging as a service appropriate for this treatment, and [the virtual hospital] as a safe and effective tool.”
It remains to be seen whether, or how, systems like these could be used with difficult-to-reach populations such as those with less access to modern technology, but experiments to test this are ongoing, especially in rural settings where access to quality health care is more challenging for people with HIV and other chronic illnesses.

Source:  http://www.poz.com/articles/hiv_emedicine_internet_761_20118.shtml

Filed under: HIV and AIDS, HIV Treatment, Medical and Research, , , , , , , , ,

Danger looming….

HIV/AIDS is shifting out of the eye of the public – it seems that the drugs available transformed a deadly disease into a chronic one. Only people deeper involved notice that we have not yet turned the tide and that still millions dying as a consequence of HIV/AIDS.

There are many reasons for things could go terribly wrong again and just as food for thoughts I want to highlight some of them coming from the political sector:

* India-EU Trade deal

According to UN AIDS 86% of people around the world taking medication the pills come as generics from India. The EU and India negotiating in the moment a free-trade deal which is a danger to the manufacturing of generic medicine because the deal delays or extends patents, requires exclusivity and looks for harsher border controls enforcement rules.

* USA deals

The USA is in the moment negotiating several deals with different partners, amongst them  Mercosur (the common market of South America), but also with Australia, Brunei, Chile, Malaysia, New Zealand, Peru, Singapore and Vietnam (Trans-Pacific partnership trade agreement). In these agreements, the USA pushes for stricter patent rights and new forms of intellectual property enforcement to intercept generics more easily. The trans pacific partnership trade agreement will be a draft for further agreements between the USA and the developing world and threatens the well-being of HIV/AIDS patients around the world while protecting the big pharmaceutical industry.

* Global AIDS Fund and research

The Global AIDS Fund lacks money and more and more countries are not paying in but negotiating one to one agreements with their perspective partner countries. The aim to bring all patients on treatment and to turn the tide is threatened. The financial crisis and the inability of the political elite to modernize economics and bring back stability means that money for research is also getting less. We not only need new drugs, the aim is still to eradicate HIV and AIDS and to create a cure for the syndrome.

 

Filed under: HIV and AIDS, HIV Treatment, Politics and Society, Reflection, , , , , , , , , ,

POZ: HIV Stem Cell Therapy in Mice Is Successful

Source: http://www.poz.com/rssredir/articles/hiv_zincfinger_sangamo_761_18693.shtml

Researchers are reporting that a new method for altering the genes of immune cells to make them resistant to HIV infection was a success in mice. The study was published online on July 2 in the journal Nature Biotechnology.
The new type of therapy, which treats stem cells with engineered zinc-finger nucleases, is designed to help the body grow new CD4 cells that don’t carry one of the key coreceptors—CCR5—that HIV requires to enter and infect a cell. In this experiment, Nathalia Holt, PhD, from the Keck School of Medicine at the University of Southern California at Los Angeles, and her colleagues compared two groups of mice that are bred to have a human immune system. The first group was given untreated stem cells. The second group received a batch of zinc-finger-treated cells.
Holt’s team found that the treated stem cells multiplied rapidly in the mice and were highly resistant to HIV infection. By comparison, the untreated cells did not spawn HIV-resistant cells, and the mice who receive the untreated cells experienced HIV-related CD4 cell losses, indicative of disease progression.
Sangamo BioSciences is developing this therapy, and small exploratory studies of zinc-finger therapy are already taking place in humans.

Filed under: HIV and AIDS, Medical and Research, , , , ,

05.10.2009 office too close to my home…

Monday morning, and instead driving to town in the morning, I just have to open a door and I am in my new office.. It is tempting to do this before being ready for the outside world.. and I guess it needs quite some discipline not to jump with a cup of coffee just into it, from the bed to the desk so to speak.

I will try to keep it separate – office work is office work and home is home. I prefer the distance between both, but that might come in due course of the next months.
I had to prepare for a workshop of Catholic AIDS network this morning, I was asked to give an overview about new care and treatment options and new developments in research. So I will speak about the Berlin patient, about the Thailand vaccine trial and other remarkable stories and new developments on the medication sector. The chairperson of HOPE Cape Town will also be there and report on the situation in South Africa, which looks much more dark than people want to believe. We have massive problems in delivering services and bringing people on treatment.
I also had a meeting at Tygerberg with the Dean of the Sport Sciences Faculty from Munich and some management members – ways of cooperation were discussed and we learned about the sport sciences in Germany and they about HOPE Cape Town in South Africa. In the evening then the celebration of the German National Day – a good one this year with lots of people I haven’t seen in ages and a good speech of the Consul General Mr. Bussmann. So quite a day, in between SA Telkom and the post office .. a full day.

I just realised this evening that my diary is full till I leave for Germany – it is amazing how little time the 8 days have.. I wish, I could extend that timeframe to get all done, what is still waiting to be worked on and finalised. Well, some night sleep has to be sacrificed to get it all done.

Filed under: HOPE Cape Town Association & Trust, Reflection, Uncategorized, , , , , , ,

03.September 2009 feeling humbled

The last two days were amazing days – so many emails, phone calls, text messages – I even did not know that so many people are following my “case” and were waiting after the cancellation of contract through the German Bishops Conference what will happen to me. Most seemed to have bid, that I will go back to Germany – others thought I will leave the church. Well, both thoughts were quite  real – real threats to my life, but thanks heaven a somehow happy end has been found.
Receiving all this positive messages, I feel indeed humbled and realise once again, what expectations people have. I personally never felt that I am doing something extraordinary but simply what was waiting along my way I picked up – and I had from the start marvellous people assisting in creating HOPE Cape Town. Living in South Africa creates other possibilities as somebody would have in Germany. But I believe that everybody has a chance to pick up a challenge along his way on earth and in doing so, change the course of this world and to assist and help people in need.

I am also a bit scared seeing the expectations of the HOPE Cape Town “family”. HOPE Cape Town is in the phase of restructuring because our possibilities and opportunities have grown so fast and big, that we have to look how to cope with all the workload. So we will add myself and a PA, a personal assistant to join HOPE Cape Town. Grass root work and research are at the ends of our working spectrum, and in between is quite a range of portfolios in need to be covered. Thanks God for the recent addition of Saadeka Williams as a full time HOPE doctor.

Also the Catholic Aids Network is in development. We had a meeting this morning as CAN has now to be registered as a NPO and PBO in South Africa in its own rights. So we met with a lawyer who is willing to do “pro bono” work and assist in getting the constitution right and the applications on the way.

With POZ, the working arm of HOPE Cape Town together with the Justice & Peace Commission of the Archdiocese of Cape Town, providing pastoral care for priests, religious and seminarians who are living with the HI virus, there is a whole new area where we have to gain expertise. Today we fixed also our meeting with the secretary of the Papal Council for health care worker in Rome; on the 18.10. we will have a meeting with the Bishop to discuss amongst other topics a possible working relationship in this field. I am very curious to see how they react in the Vatican for such a request of official support. But with or without the support, we have to face realities and we have to tackle them head on. Doing so we are also forced to look into our theology and develop our teaching accordingly. It is indeed a tricky field – but on the other hand: only tricky fields are a real challenge… 🙂

Well, it is time to go to bed – it is 2:46 am in the morning and at 6am a new working day is beginning.

Filed under: General, HOPE Cape Town Association & Trust, Reflection, , , , , , , , , , , , , , , , , , , , ,

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